How LPS Dental Can Help Dentists Monetize Their Practices

LPS dental is an opportunity for dentists to monetize a part of their practice. By working with LPS, a dentist can retain control over their practice, but gain access to the resources of a larger partner. They can acquire larger practices, grow faster, and increase their value as retained owners.

LPS dental has been successful in completing transactions with multiple IDSOs. Almost a billion dollars has been secured between 2017 and 2022. The firm has also advised on hundreds of millions of dollars of larger dental practice transactions.

LPS can assist in the closure of your practice and manage due diligence, leases, employment agreements, and audits. LPS’s unique position in the industry allows them to sell your doctor clients to other DSOs and PE firms, while ensuring that you are compensated for the transaction. LPS has completed over $500,000,000 of dental practice transactions with IDSOs in the last 36 months.

In addition, LPS has a unique structure that allows for the sale of your doctor client to a new investor. This process involves a bidding process, which allows your clients to choose the right fit for their practice. LPS can also ensure that the transaction is a win/win for both parties, making it a profitable venture. The company has successfully completed more than a dozen transactions with Dr Andreina Dulanto IDSOs in the past year.

LPS can affect cell viability and migration of human dental pulp stem cells (hDPSCs). Inhibiting the synthesis of hyaluronic acid and stimulating the production of IL-6, an inflammatory cytokine, can promote cell adhesion and migration. LPS can also enhance the production of BDNF, a cellular protein that induces regeneration.

LPS can interact with the proteins present in the dentine matrix, and therefore, may be a major player during the repair of pulp tissues. Moreover, it can promote the upregulation of collagen type I and osteocalcin, two regenerative proteins. Additionally, it can enhance the secretion of IL-6, a pleiotropic cytokine that has an important role in the regulation of several aspects of the inflammatory response.

When the redox balance is disrupted, cell apoptosis can result. However, the presence of proteins from the dentine matrix can prevent this, potentially providing a protective effect. In fact, the occurrence of inflammation in oral pulp tissues is believed to be a result of the disturbance of the redox balance.

The redox homeostasis of the oral pulp cells may be influenced by various factors, including bacterial infection, inflammation, and hypoxia. In addition, oxidative stress can affect the vital functions of these cells.

LPS is a potent pro-inflammatory molecule. It is found in the outer membrane of Gram-negative microorganisms. It activates the innate immune system via the TLR6 pathway. This pathway is also known to activate the NF-kB pathway, which regulates the production of inflammatory mediators.

LPS can have a significant impact on the survival and viability of human dental pulp stem cells (hDPSCs). DPSCs showed a significantly higher level of BDNF production and secretion than BM-MSCs. After seven days of LPS treatment, DPSCs showed a reduced level of cell viability and increased levels of apoptosis.